Severe and generalized subcutaneous calcinosis in CREST Syndrome
Case report, 168Tag this article
A 60-year-old female with severe pain in extremities had skin thickening in hands to elbows and feet to knees, loss of skin folds, microstomia and digital pitting scars. A CREST (Calcinosis, Raynaud’s phenomenon, Esophageal dysmotility, Sclerodactyly, Telangiectasias) syndrome was diagnosed. The generalized calcinosis made difficult a surgical treatment. Diltiazem alone or in combination with other drugs could be a useful therapy in patients with pronounced calcifications.
KEY WORDS: subcutaneous calcinosis; CREST Syndrome.