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Clinical Cases in mineral and bone metabolism

Generalized Lymphatic Anomaly: a case report

Case report, 71 - 74
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Complex Lymphatic Anomalies are a group of rare dis- eases characterized by a non-neoplastic proliferation of lymphatic vessels. They include Generalized Lym- phatic Anomalies and Kaposiform Lymphangiomatosis (both with involvement of visceral organs and bone with multifocal and non-progressive osteolysis) and Gorham-Stout Disease (characterized by a predominant involvement of bone with destruction of the bone ma- trix causing absorption of bone - the so-called “van- ishing bone” disease - and a far less frequent visceral involvement). Because of the rarity of these diseases, the diagnosis may be confused by their similar clini- cal presentation. We describe a case of a young man with Generalized Lymphatic Anomalies with a diffuse involvement of the skeleton and of the spleen. The aim of this report is to point out the characteristics of dif- ferent types of lymphatic anomalies to allow a correct diagnosis and a more adequate therapy.

Vol. XVI (No. 1) 2019 January - April

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