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Clinical Cases in mineral and bone metabolism

Mazabraud’s syndrome: a case report

Case report, 394 - 396
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Abstract
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Fibrous dysplasia of bone (FD) is a benign bone disease, rare, not hereditary, and characterized by an abnormal proliferation of fibroblasts and deficient differentiation of osteoblasts, leading to the replacement of trabecular
bone tissue by fibrous connective tissue. In some cases, the bone lesions are presented together with various extra-skeletal manifestations constituting specific syndromes.
Mazabraud’s syndrome represents the infrequent combination of one or more intramuscular myxomas and fibrous dysplasia. The acknowledgment would make it possible to differentiate myxomas, which are benign tumors, from malignant mesenchymal tumors with myxoid material, and in this way reduce the need for unnecessary biopsies and/or surgeries.

Vol. XV (No. 3) 2018 September - December

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