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Clinical Cases in mineral and bone metabolism

Hungry bone syndrome presenting as pathological fracture in a young boy

Case report, 375 - 380
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Hungry bone syndrome is a profound and prolonged hypocalcemia which follows parathyroidectomy. Radiological evidence of hyperparathyroidism is a known risk factor. It is more commonly reported in females with Indian studies showing higher incidence in age less than 45 as compared to 5th and 6th decade in the developed nations. We report a case of hungry bone syndrome presenting as pathological fracture of both femur following surgical removal of hyperfunctioning parathyroid adenoma in a young Indian boy of 13 years. Serological studies showed serum calcium as low as 6.09 mg/dl and DEXA score -4.2. Following diagnosis, high dose calcium supplementation was given which improved serum calcium levels over 3 months with radiological evidence of bone remineralisation and healing. We bring to notice the importance of timely recognition of this uncommon but serious adverse effect of parathyroidectomy and need for stringent treatment with calcium to prevent further bone loss and promote bone healing.

Vol. XV (No. 3) 2018 September - December

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