New insights on the role, pathogenesis, and treatment of osteoporosis and bone erosions in rheumatoid arthritis
Mini-review, 177 - 182Tag this article
Bone erosions and osteoporosis are a main problem of Rheumatoid Arthritis and even in the biologic era are unsolved problems. Many hypothesis have been formulated since today on the pathogenesis of osteoporosis and bone erosions, and a new rising hypothesis is that osteoporosis and bone erosions are part of an unique pathology of bone. Our review summarizes the state of the art on osteoporosis in RA and discusses its clinical implications in terms of risk of bone erosions.
KEY WORDS: rheumatoid arthritis; osteoporosis; bone erosions; bone metabolism; synovitis.